LNP technology is one of the widely used delivery platforms essential for the clinical translation of nucleic acid treatments. The delivery platform predominantly determines the safety, efficacy, and tissue-specificity of nucleic acid treatments. LNP delivery platform can be used in various therapeutics approaches  such as mRNA, small nucleic acids, circular RNA, gene editing and cell therapies such as CAR-T and CAR-NK.

We seek to ameliorate the toxicity and improve tissue specificity of LNPs through diversified ionizable lipid generated from our diversity-oriented lipid library (DOLL) to develop safer and effective therapeutics.